Alcresta Therapeutics

Alcresta Therapeutics

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Private Company

Total funding raised: $178M

Overview

Alcresta Therapeutics is a commercial-stage biotech company addressing a critical unmet need in enteral nutrition for patients with rare diseases. Its core technology is the RELiZORB cartridge, which contains immobilized lipase (iLipase) to break down fats in tube feeding formulas, mimicking pancreatic function. The company has achieved FDA clearance for expanded use in neonates and infants and is generating real-world evidence to support its product. Led by an experienced management team, Alcresta is positioned in the niche but essential markets of metabolic and rare diseases with a specialized drug delivery platform.

MetabolicRare Disease

Technology Platform

iLipase® immobilized lipase microbead/enzyme technology for in-line digestion of fats in enteral feeding formulas.

Funding History

4
Total raised:$178M
Debt$50M
Series C$72M
Series B$36M
Series A$20M

Opportunities

The recent FDA clearance for use in neonates and infants significantly expands the addressable patient population into critical care settings.
Generating robust real-world evidence can drive clinical adoption, secure favorable reimbursement, and strengthen the product's market position.

Risk Factors

Commercial success depends on convincing clinicians to adopt a new practice and securing adequate insurance reimbursement in a niche patient population.
The company faces potential future competition from larger players and remains subject to regulatory oversight of its commercial product.

Competitive Landscape

RELiZORB is first-to-market as the only FDA-cleared enzyme product for enteral feeding, creating a unique niche. Potential competitors include off-label use of oral pancreatic enzyme supplements or future novel devices from larger medical nutrition or gastroenterology-focused companies.