Adaptive Biotechnologies

Adaptive Biotechnologies

ADPTPhase 2
Seattle, United StatesFounded 2009adaptivebiotech.com

Adaptive Biotechnologies is translating the genetics of the adaptive immune system into clinical insights and novel therapies. Founded in 2009, the company has commercialized the clonoSEQ MRD assay and built a massive database of immune receptor sequences to fuel its drug discovery engine. Its strategic direction focuses on expanding its diagnostic portfolio and advancing its pipeline of TCR and antibody therapeutics through internal development and partnerships.

Market Cap
$2.1B
Founded
2009

ADPT · Stock Price

USD 13.58+0.84 (+6.59%)

Historical price data

AI Company Overview

Adaptive Biotechnologies is translating the genetics of the adaptive immune system into clinical insights and novel therapies. Founded in 2009, the company has commercialized the clonoSEQ MRD assay and built a massive database of immune receptor sequences to fuel its drug discovery engine. Its strategic direction focuses on expanding its diagnostic portfolio and advancing its pipeline of TCR and antibody therapeutics through internal development and partnerships.

Technology Platform

The Immune Medicine Platform uses proprietary chemistry, computational biology, and machine learning to sequence, map, pair, and characterize T-cell and B-cell receptors at scale, translating immune system genetics into a clinical database for diagnostics and drug discovery.

Pipeline Snapshot

4

4 drugs in pipeline

DrugIndicationStage
Venetoclax monotherapy + Venetoclax with anti CD20 monoclonal antibodyChronic Lymphocytic Leukemia (CLL)Phase 2
MosunetuzumabDiffuse Large B-Cell Lymphoma (DLBCL)Phase 2
Bendamustine + RituximabLymphomaPhase 2
Immunomodulatory Agent + Proteasome InhibitorMultiple MyelomaPre-clinical

Funding History

4

Total raised: $620M

IPO$300MUndisclosedJun 27, 2019
Series C$195MMatrix Capital ManagementJun 15, 2015
Series B$105MMatrix Capital ManagementJun 15, 2014
Series A$20MUndisclosedJun 15, 2009

Opportunities

Major growth opportunities include expanding clonoSEQ's FDA labels and reimbursement, leveraging its massive immune receptor database to discover first-in-class TCR and antibody therapies, and forming strategic partnerships with large biopharma companies to accelerate therapeutic development.

Risk Factors

Key risks include the company's current lack of profitability, the high-risk, long-term nature of its therapeutic pipeline, intense competition in both the MRD testing and drug discovery spaces, and the inherent platform risk if its core technology fails to deliver clinically validated candidates.

Competitive Landscape

Adaptive competes in MRD testing with Natera and Guardant Health, differentiated by clonoSEQ's FDA clearance. In immune drug discovery, it competes with platform companies like Immunai and TCR-focused firms like Immunocore, differentiated by its scale of paired receptor data and integrated diagnostic-therapeutic strategy.

Publications
19
Patents
20
Pipeline
4

Company Info

TypePlatform
Founded2009
LocationSeattle, United States
StagePhase 2
RevenueRevenue Generating

Trading

TickerADPT
ExchangeNASDAQ

Therapeutic Areas

OncologyAutoimmune DisordersInfectious DiseasesNeurodegenerative Disorders
SIMILAR COMPANIES
BASi Research Products
BASi Research Products
Pre-clinical · West Lafayette
Bay BioSciences
Bay BioSciences
Pre-clinical · San Francisco
EydisBio
EydisBio
Pre-clinical · Cambridge
3Spine
3Spine
Pre-clinical · Memphis
Belcher Pharmaceuticals
Belcher Pharmaceuticals
Pre-clinical · Miami
Is this your company?

Claim your profile to update information, add pipeline data, and connect with investors.

Claim profile