Adaptive Biotechnologies
ADPTPhase 2Adaptive Biotechnologies is translating the genetics of the adaptive immune system into clinical insights and novel therapies. Founded in 2009, the company has commercialized the clonoSEQ MRD assay and built a massive database of immune receptor sequences to fuel its drug discovery engine. Its strategic direction focuses on expanding its diagnostic portfolio and advancing its pipeline of TCR and antibody therapeutics through internal development and partnerships.
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AI Company Overview
Adaptive Biotechnologies is translating the genetics of the adaptive immune system into clinical insights and novel therapies. Founded in 2009, the company has commercialized the clonoSEQ MRD assay and built a massive database of immune receptor sequences to fuel its drug discovery engine. Its strategic direction focuses on expanding its diagnostic portfolio and advancing its pipeline of TCR and antibody therapeutics through internal development and partnerships.
Technology Platform
The Immune Medicine Platform uses proprietary chemistry, computational biology, and machine learning to sequence, map, pair, and characterize T-cell and B-cell receptors at scale, translating immune system genetics into a clinical database for diagnostics and drug discovery.
Pipeline Snapshot
44 drugs in pipeline
| Drug | Indication | Stage |
|---|---|---|
| Venetoclax monotherapy + Venetoclax with anti CD20 monoclonal antibody | Chronic Lymphocytic Leukemia (CLL) | Phase 2 |
| Mosunetuzumab | Diffuse Large B-Cell Lymphoma (DLBCL) | Phase 2 |
| Bendamustine + Rituximab | Lymphoma | Phase 2 |
| Immunomodulatory Agent + Proteasome Inhibitor | Multiple Myeloma | Pre-clinical |
Funding History
4Total raised: $620M
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Competitive Landscape
Adaptive competes in MRD testing with Natera and Guardant Health, differentiated by clonoSEQ's FDA clearance. In immune drug discovery, it competes with platform companies like Immunai and TCR-focused firms like Immunocore, differentiated by its scale of paired receptor data and integrated diagnostic-therapeutic strategy.
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