Acelot
Pre-clinicalTDP-43 is a vital protein involved in a wide range of cellular activities, most notably including regulation of mRNA splicing. It is involved in many neurodegenerative diseases and is the most critical regulator of the cascade of inflammatory reactions that leads to ALS. This cascade contributes to ongoing cellular stress and eventually the death of motor neurons.
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TDP-43 is a vital protein involved in a wide range of cellular activities, most notably including regulation of mRNA splicing. It is involved in many neurodegenerative diseases and is the most critical regulator of the cascade of inflammatory reactions that leads to ALS. This cascade contributes to ongoing cellular stress and eventually the death of motor neurons.
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