Abyssinia Biologics
Pre-clinicalSoluble oligomers of amyloid-beta (Aβ) are the most neurotoxic forms of Aβ. Unlike plaques, these soluble oligomers can disrupt synaptic function, impair neuronal communication, and lead to cognitive deficits even at low concentrations. They are thought to play a central role in the early stages of Alzheimer’s, contributing to synaptic loss and neurodegeneration as well as driving downstream pathologies like tau dysregulation.By potently and selectively targeting soluble oligomers and avoidin...
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Soluble oligomers of amyloid-beta (Aβ) are the most neurotoxic forms of Aβ. Unlike plaques, these soluble oligomers can disrupt synaptic function, impair neuronal communication, and lead to cognitive deficits even at low concentrations. They are thought to play a central role in the early stages of Alzheimer’s, contributing to synaptic loss and neurodegeneration as well as driving downstream pathologies like tau dysregulation.By potently and selectively targeting soluble oligomers and avoidin...
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