3Spine

3Spine is pioneering a new category in spinal surgery with its MOTUS total joint replacement system, designed to restore natural motion and balance in the lumbar spine as an alternative to fusion. Founded in 2015, the company has completed enrollment in a U.S. pivotal IDE clinical trial and is preparing to seek FDA Pre-Market Approval (PMA). 3Spine operates in the large and growing spinal implant market, targeting a significant segment of the degenerative spine population currently undergoing fusion procedures, with the potential to expand the market through earlier intervention.

The MOTUS platform is a first-of-kind total joint replacement (TJR) system for the lumbar spine. It is designed to biomechanically reconstruct the functional spinal unit by replacing the combined function of the intervertebral disc and the two facet joints via a posterior surgical approach, aiming to restore natural motion and sagittal balance.

3Spine is creating a new category (lumbar total joint replacement) but competes indirectly with established technologies: anterior total disc replacements (e.g., ProDisc-L, activL), posterior facet replacements (e.g., TOPS), and the vast array of spinal fusion systems. Its primary competition is the standard of care—lumbar fusion—backed by decades of surgeon familiarity and extensive vendor portfolios.