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RP2 + Bevacizumab + Atezolizumab + Durvalumab + RP2 Monotherapy

Phase 2Recruiting
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Interest: 36/100
36
Hype Score

Development Stage

✓
Pre-clinical
✓
Phase 1
3
Phase 2
4
Phase 3
5
Approved
Indication / Disease

Hepatocellular Carcinoma

Conditions

Hepatocellular Carcinoma, Biliary Tract Cancer

Trial Timeline

Aug 1, 2024 → Jul 1, 2028

NCT ID
NCT05733598

About RP2 + Bevacizumab + Atezolizumab + Durvalumab + RP2 Monotherapy

RP2 + Bevacizumab + Atezolizumab + Durvalumab + RP2 Monotherapy is a phase 2 stage product being developed by Replimune for Hepatocellular Carcinoma. The current trial status is recruiting. This product is registered under clinical trial identifier NCT05733598. Target conditions include Hepatocellular Carcinoma, Biliary Tract Cancer.

What happened to similar drugs?

5 of 20 similar drugs in Hepatocellular Carcinoma were approved

Approved (5) Terminated (2) Active (14)
✅LenvatinibEisaiApproved
✅Epirubicin + lipiodolJohnson & JohnsonApproved
✅Sorafenib (Nexavar, BAY43-9006) Sorafenib (Nexavar, BAY43-9006) + Nerison Fatty Ointment Sorafenib (Nexavar, BAY43-9006)+Neribas Fatty OintmentBayerApproved
✅Xenetix-CT perfusion imagingGuerbetApproved
✅Gadoterate meglumineGuerbetApproved
🔄Ramucirumab + PlaceboEli LillyPhase 3
🔄Atezolizumab + Bevacizumab + TiragolumabChugai PharmaceuticalPhase 3

Hype Score Breakdown

Clinical
12
Activity
15
Company
9
Novelty
0
Community
0

Clinical Trials (1)

NCT IDPhaseStatus
NCT05733598Phase 2Recruiting

Competing Products

20 competing products in Hepatocellular Carcinoma

See all competitors
ProductCompanyStageHype Score
CT-01 + EVEROLIMUSCaptor TherapeuticsPhase 1
26
ateganosine + CadonilimabMAIA BiotechnologyPhase 1
26
Ramucirumab + PlaceboEli LillyPhase 3
40
ERY974 + Tocilicumab + Atezolizumab + BevacizumabChugai PharmaceuticalPhase 1
33
Atezolizumab + Bevacizumab + TiragolumabChugai PharmaceuticalPhase 3
44
GC33(RO5137382) + SorafenibChugai PharmaceuticalPhase 1
29
CS-1008 2 mg/kg + Sorafenib + CS-1008 6/2 mg/kg + CS-1008 6/6 mg/kg + CS-1008 4 mg/kg + CS-1008 6 mg/kgDaiichi SankyoPhase 2
35
Tivantinib + PlaceboDaiichi SankyoPhase 3
40
OSI-906 + PlaceboAstellas PharmaPhase 2
27
Enzalutamide + PlaceboAstellas PharmaPhase 2
35
Enzalutamide + Enzalutamide with SorafenibAstellas PharmaPhase 1
29
Recombinant oncolytic virus M1, anti PD-1 antibody, ApatinibSun PharmaceuticalPhase 1
25
Irinotecan + Sonidegib + SorafenibSun PharmaceuticalPhase 2
42
mFOLFOX7 combined with Camrelizumab and apatinibSun PharmaceuticalPhase 2
42
camrelizumab& apatinibSun PharmaceuticalPhase 2
31
LenvatinibEisaiPre-clinical
26
Lenvatinib PillEisaiPhase 2
39
Sorafenib + SorafenibEisaiPhase 1/2
32
LenvatinibEisaiPhase 2
42
Lenvatinib + NivolumabEisaiPhase 2
35