Pembrolizumab

Phase 2Terminated

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Hype Score

Development Stage

✓

Pre-clinical

✓

Phase 1

Phase 2

Phase 3

Approved

Indication / Disease

Malignant Peripheral Nerve Sheath Tumour (MPNST)

Conditions

Malignant Peripheral Nerve Sheath Tumour (MPNST)

Trial Timeline

Jun 1, 2016 → Dec 1, 2020

NCT ID

NCT02691026

About Pembrolizumab

Pembrolizumab is a phase 2 stage product being developed by Merck for Malignant Peripheral Nerve Sheath Tumour (MPNST). The current trial status is terminated. This product is registered under clinical trial identifier NCT02691026. Target conditions include Malignant Peripheral Nerve Sheath Tumour (MPNST).

Hype Score Breakdown

Clinical

Activity

Company

Novelty

Community

Clinical Trials (20)

NCT ID	Phase	Status	Start	Completion	Indication
NCT02083484	Pre-clinical	Completed	—	—	Melanoma
NCT07302347	Phase 1/2	Recruiting	Mar 31, 2026	Dec 31, 2029	Malignant Neoplasm
NCT07089992	Phase 2	Recruiting	Dec 4, 2025	Dec 1, 2028	Sarcoma
NCT07007273	Phase 2	Recruiting	Jun 20, 2025	Jul 1, 2030	Cutaneous Sarcoma
NCT04569461	Phase 2	Withdrawn	Jun 1, 2025	Dec 1, 2026	Prostate Cancer
NCT05815927	Phase 3	Recruiting	May 23, 2025	Mar 30, 2030	Oligometastatic Squamous Cell Carcinoma of the Head and Neck
NCT05852223	Phase 2	Recruiting	Dec 20, 2024	Dec 1, 2027	Differentiated Thyroid Cancer
NCT05879120	Phase 2	Withdrawn	Jul 30, 2024	Oct 2, 2024	Recurrent Glioblastoma
NCT06004336	Phase 2	Recruiting	Oct 31, 2023	Jan 1, 2029	Oligometastatic Renal Cell Carcinoma
NCT05496036	Phase 2	Recruiting	Feb 13, 2023	Sep 30, 2027	Merkel Cell Carcinoma
NCT05131919	Phase 2	Active	Dec 22, 2022	Jul 1, 2031	Colorectal Cancer
NCT05197322	Phase 2	Recruiting	Jul 20, 2022	Dec 1, 2028	Adenocarcinoma of the Colon
NCT05406713	Phase 2	Active	Jul 13, 2022	Jan 1, 2028	Muscle Invasive Bladder Carcinoma
NCT05025813	Phase 2	Recruiting	Jun 28, 2022	Jun 1, 2027	Cutaneous Squamous Cell Carcinoma of the Head and Neck
NCT06413095	Phase 1	Completed	Jun 1, 2022	Jun 22, 2023	Head and Neck Squamous Cell Carcinoma
NCT05191472	Phase 2	Terminated	May 3, 2022	Dec 31, 2023	Multiple Myeloma
NCT05204160	Phase 2	Withdrawn	Apr 11, 2022	Feb 27, 2024	Plasma Cell Myeloma
NCT04575961	Phase 2	Active	Feb 22, 2022	Mar 1, 2028	Ovarian Cancer
NCT04417166	Phase 2	Recruiting	Feb 11, 2022	Dec 1, 2026	Lymphoma, Extranodal NK-T-Cell
NCT05188508	Phase 2	Recruiting	Jan 14, 2022	Jan 1, 2027	Glioma

Competing Products

20 competing products in Malignant Peripheral Nerve Sheath Tumour (MPNST)

See all competitors

Product	Company	Stage	Hype Score
liposomal irinotecan monotherapy + liposomal irinotecan monotherapy + Liposomal Irinotecan + rmhTNF-NC + Liposomal Irinotecan + Bevacizumab	CSPC Pharmaceutical Group Limited	Phase 1/2	40
Fulvestrant + Abemaciclib	Eli Lilly	Phase 2	52
Tadalafil + Gemcitabine	Eli Lilly	Phase 1	33
Patritumab Deruxtecan	Daiichi Sankyo	Phase 1/2	41
Tivantinib + FOLFOX	Daiichi Sankyo	Phase 1/2	41
DS-1123	Daiichi Sankyo	Phase 1	33
DS-8201a	Daiichi Sankyo	Phase 1	33
DS-5573a	Daiichi Sankyo	Phase 1	33
DS-6051b	Daiichi Sankyo	Phase 1	33
U3-1565	Daiichi Sankyo	Phase 1	33
MK-1084 + Patritumab deruxtecan + Sacituzumab tirumotecan + Cetuximab + Rescue Medications	Daiichi Sankyo	Phase 1/2	41
DS-3201b + DS-3201b	Daiichi Sankyo	Phase 1	33
DS-8895a 1 mg/kg + DS-8895a 3 mg/kg + DS-8895a 10 mg/kg	Daiichi Sankyo	Phase 1	33
ASP2998 + Pembrolizumab + Enfortumab Vedotin + Carboplatin	Astellas Pharma	Phase 1/2	41
enfortumab vedotin + pembrolizumab	Astellas Pharma	Phase 2	52
CP-461	Astellas Pharma	Phase 2	52
enfortumab vedotin	Astellas Pharma	Phase 1	33
LNF1901 Monoclonal Antibody Injection	Sun Pharmaceutical	Phase 1	33
Perampanel + Standard of Care	Eisai	Phase 1/2	41
Pembrolizumab + Lenvatinib + Placebo for lenvatinib	Eisai	Phase 3	77

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