TX45

Heart Failure with Preserved Ejection Fraction (HFpEF) and other fibrotic diseases

Phase 1Active, RecruitingNCT06474730

Key Facts

Indication
Heart Failure with Preserved Ejection Fraction (HFpEF) and other fibrotic diseases
Phase
Phase 1
Status
Active, Recruiting
Company

About Tectonic Therapeutic

Tectonic Therapeutic is advancing a pipeline of protein therapeutics designed to modulate large, multi-subunit targets like GPCRs, which have historically been challenging for drug discovery. The company's lead program, TX45, is a selective inhibitor of the relaxin receptor RXFP1, currently in Phase 1 trials for cardiovascular and fibrotic indications. Founded by world-renowned scientists and backed by leading life science investors, Tectonic leverages its unique GEODe™ platform to unlock new therapeutic opportunities in areas of high unmet medical need.

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