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CT-0508 + Pembrolizumab

HER2-overexpressing solid tumors

Phase 1Active, recruitingNCT05007379

Key Facts

Indication
HER2-overexpressing solid tumors
Phase
Phase 1
Status
Active, recruiting
Company

About Carisma Therapeutics

Carisma Therapeutics is focused on developing a new class of immunotherapies by engineering macrophages, which are innate immune cells capable of infiltrating solid tumors and modulating the tumor microenvironment. The company's lead candidate, CT-0508, is in Phase 1 clinical trials for HER2-overexpressing solid tumors, representing a first-in-class approach. Carisma has established strategic collaborations with industry leaders like Moderna and Sesen Bio to expand its platform and pipeline. Despite being a clinical-stage company with no approved products, it has attracted significant investment and attention for its innovative technology.

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Therapeutic Areas

Other HER2-overexpressing solid tumors Drugs

DrugCompanyPhase
CT-0508Carisma TherapeuticsPhase 1